>AGAP012068-PA

gi|108880479|gb|EAT44704.1| calpain, putative [Aedes aegypti]        1258   0.0  
gi|28574468|ref|NP_524016.4| Calpain-B CG8107-PA [Drosophila mel...  1088   0.0  
gi|24580499|gb|AAD04331.2| calpain [Drosophila melanogaster]         1077   0.0  
gi|125979369|ref|XP_001353717.1| GA20829-PA [Drosophila pseudoob...  1072   0.0  
gi|50513239|gb|AAT77811.1| calpain B [Gecarcinus lateralis]           951   0.0  
gi|91093008|ref|XP_968928.1| PREDICTED: similar to CG8107-PA [Tr...   944   0.0  
gi|108880478|gb|EAT44703.1| calpain, putative [Aedes aegypti]         873   0.0  
gi|600420|emb|CAA86993.1| Calpain [Drosophila melanogaster]           853   0.0  
gi|17137010|ref|NP_477047.1| Calpain-A CG7563-PB, isoform B [Dro...   853   0.0  
gi|562289|emb|CAA55298.1| calpain [Drosophila melanogaster]           853   0.0  
gi|1079058|pir||A55054 calpain (EC 3.4.22.17) large chain - frui...   853   0.0  
gi|17137012|ref|NP_477048.1| Calpain-A CG7563-PA, isoform A [Dro...   786   0.0  
gi|600422|emb|CAA86994.1| Calpain, without calmodulin-like domai...   786   0.0  
gi|56756901|gb|AAW26622.1| SJCHGC01809 protein [Schistosoma japo...   748   0.0  
gi|27765074|ref|NP_775110.1| calpain 3 isoform c [Homo sapiens] ...   659   0.0  
gi|119612956|gb|EAW92550.1| hCG40434, isoform CRA_e [Homo sapiens]    656   0.0  
gi|73999853|ref|XP_859286.1| PREDICTED: similar to calpain 3 iso...   647   0.0  
gi|73999833|ref|XP_858907.1| PREDICTED: similar to Calpain-3 (Ca...   646   0.0  
gi|123239732|emb|CAM24139.1| calpain 3 [Mus musculus]                 645   0.0  
gi|7674485|gb|AAD28255.2|AF127766_1 calpain 3; calcium activated...   645   0.0  
gi|73999859|ref|XP_859394.1| PREDICTED: similar to calpain 3 iso...   642   0.0  
gi|111598858|gb|AAH90661.1| Capn3 protein [Mus musculus] >gi|123...   642   0.0  
gi|2584822|gb|AAC04848.1| calpain Lp82 [Rattus norvegicus]            642   0.0  
gi|51011085|ref|NP_001003501.1| hypothetical protein LOC445107 [...   642   0.0  
gi|46253564|gb|AAS85758.1| gill-specific calpain [Oncorhynchus m...   640   0.0  


==> gi|108880479|gb|EAT44704.1| calpain, putative [Aedes aegypti]
          Length = 794

 Score = 1258 bits (3256), Expect = 0.0
 Identities = 596/712 (83%), Positives = 650/712 (91%), Gaps = 1/712 (0%)

Query: 104 EIPFQSISIPIAEGMFSPLGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFEDPEFPASASS 163
           +IP +    P  E ++  LG++ +G R+  DVQD+Y +R QCL++G+LFEDPEF A +SS
Sbjct: 84  QIPLKKYYTPDGEYIYR-LGEKGSGFRTRTDVQDYYVLRSQCLESGSLFEDPEFQAVSSS 142

Query: 164 LMYSKRPDRHYEWLRPHEICDGPEFFVEGFSRFDVQQGELGDCWLLAACANLTQDHKMFL 223
           LM+S+RPDRHYEWLRPHEIC+ PEFFVEGFSRFDVQQGELGDCWLLAACANLTQD KMFL
Sbjct: 143 LMFSRRPDRHYEWLRPHEICENPEFFVEGFSRFDVQQGELGDCWLLAACANLTQDQKMFL 202

Query: 224 RVVPEDNSFEDGYAGVFHFRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSEQNEFWSALLE 283
           RVVPEDNSFED YAG+FHFRFWQYG+WVDVVIDDRLPTYRG+LIYMRSSE+NEFWSALLE
Sbjct: 203 RVVPEDNSFEDDYAGIFHFRFWQYGRWVDVVIDDRLPTYRGELIYMRSSEKNEFWSALLE 262

Query: 284 KAYAKLHGSYESLRGGTTCEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKGFKRNSMFGCS 343
           KAYAKLHGSYE+L+GGTTCEAMEDFTGGV EMYDLKDQTPPNLF IIEKGF+RNSMF CS
Sbjct: 263 KAYAKLHGSYEALKGGTTCEAMEDFTGGVTEMYDLKDQTPPNLFAIIEKGFQRNSMFACS 322

Query: 344 IEADPHVLEAETPEGLIRGHAYSITKIQLVDIETPGRSGKIPLIRLRNPWGNEAEWNGPW 403
           IE DPHV EAET EGLIRGHAYSITKIQLVDI TPG SGKIPLIRLRNPWGNEAEWNG W
Sbjct: 323 IEPDPHVTEAETREGLIRGHAYSITKIQLVDIVTPGTSGKIPLIRLRNPWGNEAEWNGAW 382

Query: 404 SDKSPEWRYIPDEQKQELGLNFDHDGEFWMSYRDFTRYFDRMEICNLSPDSLSDDEMTRG 463
           SD+S EWRYIPDEQK+ELGLNFD DGEFWMSYRDFTRYFDR+EICNLSPDSLS++++ RG
Sbjct: 383 SDQSAEWRYIPDEQKEELGLNFDCDGEFWMSYRDFTRYFDRIEICNLSPDSLSEEQVNRG 442

Query: 464 KISWEMSMFEGEWAVGTTAGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGNCTVIIALLQK 523
           K+ WEMS FEGEWA+G+TAGGCRNYL TFWHNPQYV+ LDDPDEDD+EG CTVIIAL+QK
Sbjct: 443 KLRWEMSTFEGEWAIGSTAGGCRNYLQTFWHNPQYVVHLDDPDEDDDEGKCTVIIALMQK 502

Query: 524 NRRSRRNMGVECLTIGFAVYRVTERDLAQKPLKMNFFKYNASAARSPAFINLREVSCRFK 583
           NRRSRRNMGV+CLTIGFAVYRVTERDLAQKPLKMNFFKYNAS ARSPAFINLREVSCRFK
Sbjct: 503 NRRSRRNMGVDCLTIGFAVYRVTERDLAQKPLKMNFFKYNASVARSPAFINLREVSCRFK 562

Query: 584 LPPGTYVIVPSTFEPNEEGEFIIRVFSETANSMMENDDNVGVGDLDDRIAPDVPGYVQPS 643
           LPPG Y+IVPSTFEPNEEGEF+IRVFSE  NSM END+ VGVG++DDRIAPDVP   QPS
Sbjct: 563 LPPGEYLIVPSTFEPNEEGEFLIRVFSECKNSMEENDEEVGVGEIDDRIAPDVPVPSQPS 622

Query: 644 PQRQAMERLFLDVAGADGEVDWVELKRILDHSFRDDNISSEGFSKDVCRAMVAMLDVDHT 703
           P RQAMERLFLDVAGADGEVDWVELKRILDHSFRD +  S GFSKDVCR+MVAMLD D +
Sbjct: 623 PARQAMERLFLDVAGADGEVDWVELKRILDHSFRDVDQGSSGFSKDVCRSMVAMLDTDQS 682

Query: 704 GKLGFEEFQQLLTDIAKWKAVFKLYDTEGSGRLSPFQLREALNSAGYHLNNRILNALVHR 763
           GKLGFEEFQ LLTDI+KWKAVFKLYD + +GRLS F+LREAL+SAGYHLNNRILN LVHR
Sbjct: 683 GKLGFEEFQSLLTDISKWKAVFKLYDQDQTGRLSAFELREALHSAGYHLNNRILNGLVHR 742

Query: 764 YGSRSGTIPFDDFIMCAVKIKTMIEIFRERDTDGTNQATFSMDEWVEKTLYS 815
           YGSR G+I FDDFIMCAVKIKTMI+IFRERDT+GTN ATFSMDEWVEKTLYS
Sbjct: 743 YGSRDGSIAFDDFIMCAVKIKTMIDIFRERDTEGTNMATFSMDEWVEKTLYS 794



==> gi|28574468|ref|NP_524016.4| Calpain-B CG8107-PA [Drosophila
           melanogaster] >gi|62510466|sp|Q9VT65|CANB_DROME Calpain
           B (Calcium-activated neutral proteinase B) (CANP B)
           [Contains: Calpain B catalytic subunit 1; Calpain B
           catalytic subunit 2] >gi|23093759|gb|AAF50189.2|
           CG8107-PA [Drosophila melanogaster]
          Length = 925

 Score = 1088 bits (2813), Expect = 0.0
 Identities = 525/845 (62%), Positives = 635/845 (75%), Gaps = 36/845 (4%)

Query: 1   PAAFAQSPPASQWPTVPTPGSSGYSSLNPSISGQSLSYGFNPNVMPALPDSGAGYPPAGN 60
           P   A S PA      P PGS  Y SL PS +  SL Y   P    A   +G  YP    
Sbjct: 87  PVPEAPSAPAPYPSATPYPGSGLYPSL-PSANVSSLPY---PTAPMAPYPTGMPYPTGMP 142

Query: 61  Q--LPYPTMGFAGF--------GSPMDYT-MPNLP----------------PPVPDALLR 93
           Q  LPYP    A +        G PM Y  MP  P                PP   A  +
Sbjct: 143 QPNLPYPAAPLAPYPSAMPGLPGMPMPYAPMPTSPAPQHNIGFPALPYPTAPPPESAPTQ 202

Query: 94  GAEPAAATCEEIPFQSISIPIAEGMFSPLGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFE 153
             EP+    E + F S+ +P  + MF       + +++S    DF  +R  CL NGT+FE
Sbjct: 203 EEEPSVGVAE-LSFTSVKVPENQNMFWMGRKATSARQNSVSKGDFQSLRDSCLANGTMFE 261

Query: 154 DPEFPASASSLMYSKRPDRHYEWLRPHEICDGPEFFVEGFSRFDVQQGELGDCWLLAACA 213
           DP+FPA+ +SLMYS+RPDR+YEWLRP +I D P+FFVEG+SRFDVQQGELGDCWLLAA A
Sbjct: 262 DPDFPATNASLMYSRRPDRYYEWLRPGDIADDPQFFVEGYSRFDVQQGELGDCWLLAAAA 321

Query: 214 NLTQDHKMFLRVVPEDNSFEDGYAGVFHFRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSE 273
           NLTQD  +F RV+P D  F++ YAG+FHF+FWQYGKWV+VVIDDRLPTY G+LIYM S+E
Sbjct: 322 NLTQDSTLFFRVIPPDQDFQENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTE 381

Query: 274 QNEFWSALLEKAYAKLHGSYESLRGGTTCEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKG 333
           +NEFWSALLEKAYAKLHGSYE+L+GGTTCEAMEDFTGGV E YD+K+  PPNLF I+ K 
Sbjct: 382 KNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKE-APPNLFSIMMKA 440

Query: 334 FKRNSMFGCSIEADPHVLEAETPEGLIRGHAYSITKIQLVDIETPGRSGKIPLIRLRNPW 393
            +R SM GCS+E DPHVLEAETP+GLIRGHAYSITK+ L+DI TP R GK+P+IR+RNPW
Sbjct: 441 AERGSMMGCSLEPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPW 500

Query: 394 GNEAEWNGPWSDKSPEWRYIPDEQKQELGLNFDHDGEFWMSYRDFTRYFDRMEICNLSPD 453
           GN+AEW+GPWSD SPEWR+IP+  K+E+GLNFD DGEFWMS++DF  +FDR+EICNLSPD
Sbjct: 501 GNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPD 560

Query: 454 SLSDDEMTRGKISWEMSMFEGEWAVGTTAGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGN 513
           SL++D+    +  WEMSMFEGEW  G TAGGCRN+L+TFWHNPQY+I L+DPD++D++G 
Sbjct: 561 SLTEDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDDGK 620

Query: 514 CTVIIALLQKNRRSRRNMGVECLTIGFAVYRVTERDLAQKPLKMNFFKYNASAARSPAFI 573
           CT I+AL+QKNRRS+RN+G++CLTIGFA+Y +T+RD+  KP  +NFFKY AS ARSP FI
Sbjct: 621 CTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFI 680

Query: 574 NLREVSCRFKLPPGTYVIVPSTFEPNEEGEFIIRVFSETANSMMENDDNVGVGDLDDRIA 633
           N REV  RFKLPPG Y+IVPSTF+PNEEGEFIIRVFSET N+M ENDD VG G+ DDRIA
Sbjct: 681 NTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIA 740

Query: 634 PDVPGYV---QPSPQRQAMERLFLDVAGADGEVDWVELKRILDHSFRDDNISSEGFSKDV 690
           P +P      +  PQR A+ RLF  VAG+D EVDW ELKRILDHS RD  + S+GFSKD 
Sbjct: 741 PSLPPPTPKEEDDPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMVGSDGFSKDA 800

Query: 691 CRAMVAMLDVDHTGKLGFEEFQQLLTDIAKWKAVFKLYDTEGSGRLSPFQLREALNSAGY 750
            R+MVAMLD D +G+LGFEEF+ LLTDIAKW+AVFKLYDT  +G +  F LR ALNSAGY
Sbjct: 801 VRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGY 860

Query: 751 HLNNRILNALVHRYGSRSGTIPFDDFIMCAVKIKTMIEIFRERDTDGTNQATFSMDEWVE 810
           HLNNR+LNAL HRYGSR G IPFDDF+MCA+K++T IE+FRERDTD ++ A F++D+W+E
Sbjct: 861 HLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLE 920

Query: 811 KTLYS 815
           +T+YS
Sbjct: 921 RTIYS 925



==> gi|24580499|gb|AAD04331.2| calpain [Drosophila melanogaster]
          Length = 925

 Score = 1077 bits (2785), Expect = 0.0
 Identities = 519/845 (61%), Positives = 633/845 (74%), Gaps = 36/845 (4%)

Query: 1   PAAFAQSPPASQWPTVPTPGSSGYSSLNPSISGQSLSYGFNPNVMPALPDSGAGYPPAGN 60
           P   A S PA      P PGS  Y SL PS +  SL Y   P    A   +G  YP    
Sbjct: 87  PVPEAPSAPAPYPSATPYPGSGLYPSL-PSANVSSLPY---PTAPMAPYPTGMPYPTGMP 142

Query: 61  Q--LPYPTMGFAGF--------GSPMDYT-MPNLP----------------PPVPDALLR 93
           Q  LPYP    A +        G PM Y  MP  P                PP   A  +
Sbjct: 143 QPNLPYPAAPLAPYPSAMPGLPGMPMPYAPMPTSPAPQHNIGFPALPYPTAPPPESAPTQ 202

Query: 94  GAEPAAATCEEIPFQSISIPIAEGMFSPLGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFE 153
             EP+    E + F S+ +P  + MF       + +++S    DF  +R  CL NGT+FE
Sbjct: 203 EEEPSVGVAE-LSFTSVKVPENQNMFWMGRKATSARQNSVSKGDFQSLRDSCLANGTMFE 261

Query: 154 DPEFPASASSLMYSKRPDRHYEWLRPHEICDGPEFFVEGFSRFDVQQGELGDCWLLAACA 213
           DP+FPA+ +SLMYS+RPDR+YEWLRP +I   P+FFVEG+SRFDVQQGELG+CWLLAA A
Sbjct: 262 DPDFPATNASLMYSRRPDRYYEWLRPGDIAGDPQFFVEGYSRFDVQQGELGECWLLAAAA 321

Query: 214 NLTQDHKMFLRVVPEDNSFEDGYAGVFHFRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSE 273
           NLTQD  +F RV+P D  F++ YAG+FHF+FWQYGKWV+VVIDDRLPTY G+LIYM S+E
Sbjct: 322 NLTQDSTLFFRVIPPDQDFQENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTE 381

Query: 274 QNEFWSALLEKAYAKLHGSYESLRGGTTCEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKG 333
           +NEFWSALLEKAYAKLHGSYE+L+GGTTCEAMEDFTGGV E YD+K+  PP LF I+ K 
Sbjct: 382 KNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKE-APPILFSIMMKA 440

Query: 334 FKRNSMFGCSIEADPHVLEAETPEGLIRGHAYSITKIQLVDIETPGRSGKIPLIRLRNPW 393
            +R SM GCS+E DPHVLEAETP+GLIRGHAYSITK+ L+DI TP R GK+P+IR+RNPW
Sbjct: 441 AERGSMMGCSLEPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPW 500

Query: 394 GNEAEWNGPWSDKSPEWRYIPDEQKQELGLNFDHDGEFWMSYRDFTRYFDRMEICNLSPD 453
           GN+AEW+GPWSD SPEWR+IP+  K+E+GLNFD DG+FWMS+++F  +FDR+EICNLSPD
Sbjct: 501 GNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGDFWMSFQEFLNHFDRVEICNLSPD 560

Query: 454 SLSDDEMTRGKISWEMSMFEGEWAVGTTAGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGN 513
           SL++D+    +  WEMSMFEGEW  G TAGGCRN+L+TFWHNPQY+I L+DPD++D++G 
Sbjct: 561 SLTEDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDDGK 620

Query: 514 CTVIIALLQKNRRSRRNMGVECLTIGFAVYRVTERDLAQKPLKMNFFKYNASAARSPAFI 573
           CT I+AL+QKNRRS+RN+G++CLTIGFA+Y +T+RD+  KP  +NFFKY AS ARSP FI
Sbjct: 621 CTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFI 680

Query: 574 NLREVSCRFKLPPGTYVIVPSTFEPNEEGEFIIRVFSETANSMMENDDNVGVGDLDDRIA 633
           N REV  RFKLPPG Y+IVPSTF+PNEEGEFIIRVFSET N+M ENDD VG G+ DDRIA
Sbjct: 681 NTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIA 740

Query: 634 PDVPGYV---QPSPQRQAMERLFLDVAGADGEVDWVELKRILDHSFRDDNISSEGFSKDV 690
           P +P      +  PQR A+ RLF  VAG+D EVDW ELKRILDHS RD  + S+GFSKD 
Sbjct: 741 PSLPPPTPKEEDDPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMVGSDGFSKDA 800

Query: 691 CRAMVAMLDVDHTGKLGFEEFQQLLTDIAKWKAVFKLYDTEGSGRLSPFQLREALNSAGY 750
            R+MVAMLD D +G+LGFEEF+ LLTDIAKW+AVFKLYDT  +G +  F LR ALNSAGY
Sbjct: 801 VRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGY 860

Query: 751 HLNNRILNALVHRYGSRSGTIPFDDFIMCAVKIKTMIEIFRERDTDGTNQATFSMDEWVE 810
           HLNNR+LNAL HRYGSR G IPFDDF+MCA+K++T IE+FRERDTD ++  +F++D+W+E
Sbjct: 861 HLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTGSFNLDDWLE 920

Query: 811 KTLYS 815
           +T+YS
Sbjct: 921 RTIYS 925



==> gi|125979369|ref|XP_001353717.1| GA20829-PA [Drosophila
           pseudoobscura] >gi|54640699|gb|EAL29450.1| GA20829-PA
           [Drosophila pseudoobscura]
          Length = 931

 Score = 1072 bits (2773), Expect = 0.0
 Identities = 521/842 (61%), Positives = 635/842 (75%), Gaps = 33/842 (3%)

Query: 2   AAFAQSPPASQWP-TVPTPGSSGYSSLNPSISGQSLSYGFNPNV-------MPALPDSGA 53
           A+ A  P A+ +P   P PG+  Y SL PS S  SL Y   P          P++P  G 
Sbjct: 95  ASAAPYPGAAPYPGAAPYPGAGLYPSL-PSASS-SLPYPSAPLAPYPSSMPYPSMPQPGL 152

Query: 54  GYPPAGNQLPYPTMGFAGFGSPMDYT-------------MPNLP----PPVPDALLRGAE 96
            YP A    PYP    A    PM Y               P+LP    PP   A  +  E
Sbjct: 153 PYPSAP-LAPYPNANTAFPSMPMPYVPLPTSPAPQQAGGFPSLPYPTAPPPASAPTQEEE 211

Query: 97  PAAATCEEIPFQSISIPIAEGMFSPLGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFEDPE 156
           P+    E + F S+ +P  + MF       + +++S    DF  +R  C+ NGT+FEDP+
Sbjct: 212 PSVGIAE-LSFTSVKVPENQNMFWMGRKATSTRQTSIRGDDFASLRDSCVINGTMFEDPD 270

Query: 157 FPASASSLMYSKRPDRHYEWLRPHEICDGPEFFVEGFSRFDVQQGELGDCWLLAACANLT 216
           FPA+ +SLM+SKRPDR+ EWLRP +I   P+FFVEG+SRFDVQQGELGDCWLLAA ANLT
Sbjct: 271 FPANNASLMFSKRPDRYIEWLRPGDIVGDPQFFVEGYSRFDVQQGELGDCWLLAAAANLT 330

Query: 217 QDHKMFLRVVPEDNSFEDGYAGVFHFRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSEQNE 276
           QD  +F RV+P D SF++ YAG+FHF+FWQYGKWV+VVIDDRLPTY G+LIYM S+E+NE
Sbjct: 331 QDSTLFFRVIPPDQSFQENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTERNE 390

Query: 277 FWSALLEKAYAKLHGSYESLRGGTTCEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKGFKR 336
           FWSALLEKAYAKLHGSYE+L+GGTTCEAMEDFTGGV E YD+K+  PPNLF I+ K  +R
Sbjct: 391 FWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKE-APPNLFSIMMKAAER 449

Query: 337 NSMFGCSIEADPHVLEAETPEGLIRGHAYSITKIQLVDIETPGRSGKIPLIRLRNPWGNE 396
            SM GCS+E DPHVLEAET EGLIRGHAYSITK+ L+DI TP R GK+P+IR+RNPWGN+
Sbjct: 450 GSMMGCSLEPDPHVLEAETREGLIRGHAYSITKVCLMDISTPNRQGKMPMIRMRNPWGND 509

Query: 397 AEWNGPWSDKSPEWRYIPDEQKQELGLNFDHDGEFWMSYRDFTRYFDRMEICNLSPDSLS 456
           AEW+GPWSD SPEWR+IP+  K+E+GLNFD DGEFWMS++DF  +FDR+EICNL+PDSL+
Sbjct: 510 AEWSGPWSDSSPEWRFIPEHVKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLNPDSLT 569

Query: 457 DDEMTRGKISWEMSMFEGEWAVGTTAGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGNCTV 516
           +D+    +  WEMSMFEGEW  G TAGGCRN+L+TFWHNPQYVI L+DPD++D++G CTV
Sbjct: 570 EDQQNSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYVISLEDPDDEDDDGKCTV 629

Query: 517 IIALLQKNRRSRRNMGVECLTIGFAVYRVTERDLAQKPLKMNFFKYNASAARSPAFINLR 576
           I+AL+QKNRRS+R +G++CLTIGFA+Y +T+RDL  KP  +NFFKY AS ARSP FIN R
Sbjct: 630 IVALMQKNRRSKRKVGIDCLTIGFAIYHLTDRDLQVKPQALNFFKYRASVARSPHFINTR 689

Query: 577 EVSCRFKLPPGTYVIVPSTFEPNEEGEFIIRVFSETANSMMENDDNVGVGDLDDRIAPDV 636
           EV  RFKLPPG Y+IVPSTF+PNEEGEFIIRVFSET N+M ENDD VG GD DDRIAP +
Sbjct: 690 EVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETMNNMEENDDEVGFGDTDDRIAPAL 749

Query: 637 PGYV---QPSPQRQAMERLFLDVAGADGEVDWVELKRILDHSFRDDNISSEGFSKDVCRA 693
           P      +  PQR A+ RLF  VAG+D EVDW ELKRILDHS RD  + ++GFSKD  R+
Sbjct: 750 PPPTPKEEDDPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMMGTDGFSKDAVRS 809

Query: 694 MVAMLDVDHTGKLGFEEFQQLLTDIAKWKAVFKLYDTEGSGRLSPFQLREALNSAGYHLN 753
           MVAMLD D +G+LGF+EF+ LLTDIAKW+AVFKLYDT  +G +  F LR ALNSAGYHLN
Sbjct: 810 MVAMLDKDRSGRLGFDEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLN 869

Query: 754 NRILNALVHRYGSRSGTIPFDDFIMCAVKIKTMIEIFRERDTDGTNQATFSMDEWVEKTL 813
           NR+LNAL HRYGS  G IPFDDF+MCA+K++T IE+FRERDTD ++ A F++D+W+E+T+
Sbjct: 870 NRLLNALAHRYGSHEGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLERTI 929

Query: 814 YS 815
           YS
Sbjct: 930 YS 931



==> gi|50513239|gb|AAT77811.1| calpain B [Gecarcinus lateralis]
          Length = 754

 Score =  951 bits (2459), Expect = 0.0
 Identities = 438/698 (62%), Positives = 557/698 (79%), Gaps = 5/698 (0%)

Query: 119 FSPLGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFEDPEFPASASSLMYSKRPDRHYEWLR 178
           F   G+R +G R    VQDFY++RQQCLDNGTLFEDP+FPA  +S+ +S+ P + +EW R
Sbjct: 61  FYMFGERGSGLRPRGQVQDFYELRQQCLDNGTLFEDPDFPAEDTSIFFSRSPPKPFEWKR 120

Query: 179 PHEICDGPEFFVEGFSRFDVQQGELGDCWLLAACANLTQDHKMFLRVVPEDNSFEDGYAG 238
           PHEI D P+ F++G +RFDV+QGELGDCWLLAA ANLT + ++F ++VP D  F D YAG
Sbjct: 121 PHEITDEPQLFIDGATRFDVKQGELGDCWLLAAVANLTLNRRLFYQIVPSDQGFGDNYAG 180

Query: 239 VFHFRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSEQNEFWSALLEKAYAKLHGSYESLRG 298
           +FHFRFWQYG+WVDVV+DDRLPT+ G+L++M S E+NEFWSAL EKAYAKLHGSYE+L+G
Sbjct: 181 IFHFRFWQYGRWVDVVVDDRLPTFYGRLVFMHSEEKNEFWSALAEKAYAKLHGSYEALKG 240

Query: 299 GTTCEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKGFKRNSMFGCSIEADPHVLEAETPEG 358
           GTTCEAMEDFTGGV+E+YDL  + PPNLF I+ K ++R S+ GCSI+ DP+V+EA    G
Sbjct: 241 GTTCEAMEDFTGGVSEIYDL-TKAPPNLFNIMLKAYQRGSLMGCSIDPDPNVVEARCDNG 299

Query: 359 LIRGHAYSITKIQLVDIETPGRSGKIPLIRLRNPWGNEAEWNGPWSDKSPEWRYIPDEQK 418
           LIRGHAYSIT+I+  DIETP  SGKIPL+R+RNPWGNEAEW G WSDKSPEW++IP E+K
Sbjct: 300 LIRGHAYSITRIKYCDIETPRVSGKIPLVRIRNPWGNEAEWVGSWSDKSPEWQFIPPEEK 359

Query: 419 QELGLNFDHDGEFWMSYRDFTRYFDRMEICNLSPDSLSDDEMTRG-KISWEMSMFEGEWA 477
           +E+GL F+HDGEFWMS++DF   F  +E+ NL+PDSL D+++T   +  WEMS+FEG W 
Sbjct: 360 EEMGLTFEHDGEFWMSFKDFLTNFTMLEMTNLNPDSLEDEDITGSVQHKWEMSVFEGAWI 419

Query: 478 VGTTAGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGNCTVIIALLQKNRRSRRNMGVECLT 537
            G+TAGGCRN+LD+FWHNPQY I L + D+DD++  CTVI+AL+QKNRRS+R +G+ECLT
Sbjct: 420 RGSTAGGCRNFLDSFWHNPQYRITLSEVDDDDDDNKCTVIVALMQKNRRSQRKLGLECLT 479

Query: 538 IGFAVYRVTERDLAQKPLKMNFFKYNASAARSPAFINLREVSCRFKLPPGTYVIVPSTFE 597
           IGFA+Y + + D   +PL +NFFKY+AS ARSP+FIN+REVSCRFKLPPGTY IVPSTFE
Sbjct: 480 IGFAIYHLRDPDSVPRPLDLNFFKYSASVARSPSFINMREVSCRFKLPPGTYCIVPSTFE 539

Query: 598 PNEEGEFIIRVFSETANSMMENDDNVGVGDLDDRIAPDVPGYVQPSPQRQAMERLFLDVA 657
           PNE+GEFI+RVFSE AN M END++VG G +DDR+ P+       + +R  +   F  VA
Sbjct: 540 PNEDGEFILRVFSEKANEMEENDEDVGFGQVDDRVRPEDDAQEVEADER--INAFFRKVA 597

Query: 658 GADGEVDWVELKRILDHSFRDDNISSEGFSKDVCRAMVAMLDVDHTGKLGFEEFQQLLTD 717
           G D E+DW EL+ +L+ + + +  + EGFSKDVCR+M+AM+DVD +GKLG +EF QL  D
Sbjct: 598 GDDLEIDWKELQDVLNFALKRE-FNFEGFSKDVCRSMIAMMDVDRSGKLGLQEFLQLWMD 656

Query: 718 IAKWKAVFKLYDTEGSGRLSPFQLREALNSAGYHLNNRILNALVHRYGSRSGTIPFDDFI 777
           I  WK  FKLYD + SG+L  F+LR+ALNSAGY LNN I +AL+ RYG R G + FDDFI
Sbjct: 657 IRVWKNAFKLYDKDSSGQLCSFELRQALNSAGYRLNNHICDALMLRYGDRDGKVSFDDFI 716

Query: 778 MCAVKIKTMIEIFRERDTDGTNQATFSMDEWVEKTLYS 815
           MC+VK+KTM+EIF+ERD D T +ATFS++EWVE T+YS
Sbjct: 717 MCSVKLKTMMEIFQERDPDRTTKATFSLEEWVENTMYS 754



==> gi|91093008|ref|XP_968928.1| PREDICTED: similar to CG8107-PA
            [Tribolium castaneum]
          Length = 1115

 Score =  944 bits (2440), Expect = 0.0
 Identities = 445/695 (64%), Positives = 549/695 (78%), Gaps = 10/695 (1%)

Query: 123  GDRNAGQRSSFDVQDFYQIRQQCLDNGTLFEDPEFPASASSLMYSKRPDRHYEWLRPHEI 182
            G++ +G ++    QDFY++R QCL  G LFEDPEFP + SSL YS RPDR +EW RP EI
Sbjct: 427  GEQGSGFQAKKGSQDFYELRDQCLQRGELFEDPEFPPTDSSLFYSHRPDRRFEWRRPGEI 486

Query: 183  CDGPEFFVEGFSRFDVQQGELGDCWLLAACANLTQDHKMFLRVVPEDNSFEDGYAGVFHF 242
             D P+ FVEGFSRFDVQQGELGDCWLLAA ANLT   ++F ++VP+D  F++ YAG+FHF
Sbjct: 487  VDNPQLFVEGFSRFDVQQGELGDCWLLAAVANLTLYRRLFFQIVPDDQGFDENYAGIFHF 546

Query: 243  RFWQYGKWVDVVIDDRLPTYRGQLIYMRSSEQNEFWSALLEKAYAKLHGSYESLRGGTTC 302
            RFWQYG+W+DVVIDDRLPTYRG+L+++ S+E NEFWSALLEKAYAKLHGSYE+L+GG+TC
Sbjct: 547  RFWQYGRWIDVVIDDRLPTYRGELVFLHSTEANEFWSALLEKAYAKLHGSYEALKGGSTC 606

Query: 303  EAMEDFTGGVAEMYDLKDQTPPNLFEIIEKGFKRNSMFGCSIEADPHVLEAETPEGLIRG 362
            EAMEDFTGGV EMY+L D  PPNLF+II K ++R S+ GCSIE DP VLEA+TPEGLIRG
Sbjct: 607  EAMEDFTGGVTEMYEL-DAAPPNLFKIISKAYERWSLMGCSIEPDPDVLEAQTPEGLIRG 665

Query: 363  HAYSITKIQLVDIETPGRSGKIPLIRLRNPWGNEAEWNGPWSDKSPEWRYIPDEQKQELG 422
            HAYSITK+Q V+I TP  SGKIPL+RLRNPWGNE+EWNG WSD SPEW YI D  K+ELG
Sbjct: 666  HAYSITKVQYVNITTPNVSGKIPLLRLRNPWGNESEWNGAWSDHSPEWHYISDSDKEELG 725

Query: 423  LNFDHDGEFWMSYRDFTRYFDRMEICNLSPDSLSDDEMTRGK-ISWEMSMFEGEWAVGTT 481
            LNFD DGEFWMS++DF ++F+R+EICNL+PDSL++DE+T G+   W MS+FEGEW  G T
Sbjct: 726  LNFDADGEFWMSFKDFQQHFNRIEICNLNPDSLAEDELTEGRNKKWVMSVFEGEWVRGVT 785

Query: 482  AGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGNCTVIIALLQKNRRS-RRNMGVECLTIGF 540
            AGGCRN+LDTF HNPQY + LD+ DE D++  CT+I+AL+QKNRR  RR++G + LTIGF
Sbjct: 786  AGGCRNFLDTFSHNPQYRVTLDEVDEGDDDDKCTLIVALMQKNRRQMRRSVGPDLLTIGF 845

Query: 541  AVYRVTERDLAQKPLKMNFFKYNASAARSPAFINLREVSCRFKLPPGTYVIVPSTFEPNE 600
            A+Y +   D A KPL +NFFKYNAS ARSP+FINLREVSCRFKLP GTY IVPSTF+PNE
Sbjct: 846  AIYYLPYPDRAPKPLDLNFFKYNASVARSPSFINLREVSCRFKLPRGTYCIVPSTFDPNE 905

Query: 601  EGEFIIRVFSETANSMMENDDNVGVGDLDDRIAPDVP-GYVQPSPQRQAMERLFLDVAGA 659
            EGEF++RVFSE  N+M END  +G+      ++  VP   ++   +  A+ +LF ++AG 
Sbjct: 906  EGEFLLRVFSEHQNNMEENDQQIGL------VSEPVPEPTLEEKKENDAIFKLFKNIAGK 959

Query: 660  DGEVDWVELKRILDHSFRDDNISSEGFSKDVCRAMVAMLDVDHTGKLGFEEFQQLLTDIA 719
            D EVDW ELK ILDH  R     + GFSKDVCR+M+AMLDVD TGKL FEEF++L   I 
Sbjct: 960  DEEVDWKELKEILDHYTRKVKTQNRGFSKDVCRSMIAMLDVDRTGKLNFEEFKRLWESIR 1019

Query: 720  KWKAVFKLYDTEGSGRLSPFQLREALNSAGYHLNNRILNALVHRYGSRSGTIPFDDFIMC 779
             WK++FK +D   SG L+ F+LR AL SAGY LNN ILN L+HRYG++S  I FDDFIMC
Sbjct: 1020 HWKSIFKQHDVNESGTLTGFELRNALTSAGYSLNNHILNILMHRYGNKSNEIEFDDFIMC 1079

Query: 780  AVKIKTMIEIFRERDTDGTNQATFSMDEWVEKTLY 814
            AVK+K MIE+F++  +   + ATF++ +W+E TLY
Sbjct: 1080 AVKLKIMIELFKQVASPDADAATFNLSDWIENTLY 1114



==> gi|108880478|gb|EAT44703.1| calpain, putative [Aedes aegypti]
          Length = 799

 Score =  873 bits (2255), Expect = 0.0
 Identities = 438/759 (57%), Positives = 542/759 (71%), Gaps = 79/759 (10%)

Query: 128 GQRSSFDVQDFYQIRQQCLDNGTLFEDPEFPASASSLMYSKRPDRHYEWLRPHEICDGPE 187
           G RS+ + QDFY +R++CL +GTLFEDPEFPA+ SSL +S     + +WLRP +I   P 
Sbjct: 47  GPRSA-EAQDFYALRKRCLRSGTLFEDPEFPANNSSLTFSGESRSNLKWLRPSQISPDPR 105

Query: 188 FFVEGFSRFDVQQGELGDCWLLAACANLTQDHKMFLRVVPEDNSFEDGYAGVFHFRFWQY 247
           FF   +SRFDV QGELGDCWLLAA ANLTQD ++F RVVPEDNSF+  YAG+FHFRFW++
Sbjct: 106 FFEASYSRFDVNQGELGDCWLLAAAANLTQDPQLFTRVVPEDNSFKQDYAGIFHFRFWRF 165

Query: 248 GKWVDVVIDDRLPTYRGQLIYMRSSEQNEFWSALLEKAYAKLHGSYESLRGGTTCEAMED 307
           G+W DVVIDDRLPT  G+L+YMRS+E NEFWSALLEKAYAKL GSYE+LRGG+  EAM D
Sbjct: 166 GQWCDVVIDDRLPTVNGKLVYMRSTEDNEFWSALLEKAYAKLFGSYEALRGGSASEAMVD 225

Query: 308 FTGGVAEMYDLKDQTPPNLFEIIEKGFKRNSMFGCSIEADPHVLEAETPEGLIRGHAYSI 367
           FTGG+AE Y++KD  P +LF+IIEKGF+ ++MF CS+E DP+  EAETP+GLIRGHAYS+
Sbjct: 226 FTGGIAESYEMKD-VPKDLFQIIEKGFRSHAMFACSLEPDPYKPEAETPQGLIRGHAYSL 284

Query: 368 TKIQLVDIETPGRSGKIPLIRLRNPWGNEAEWNGPWSDKSPEWRYIPDEQKQELGLNFDH 427
           T  ++VDI+TP   GKIPL+RLRNPWGN  EWNG WSDKSPEW+YIP+E K+E+GL F+ 
Sbjct: 285 TMAKMVDIQTPNVKGKIPLLRLRNPWGNANEWNGAWSDKSPEWKYIPEETKREIGLIFEL 344

Query: 428 DGEFWMSYRDFTRYFDRMEICNLSPDSLSDDEMTRGKISWEMSMFEGEWAVGTTAGGCRN 487
           DGEFWMSY+DF +YFDR+E+CN+SPD     +   G   W+ S FEGEW +G+TAGGCRN
Sbjct: 345 DGEFWMSYQDFVKYFDRIEMCNMSPDCPIIRQ--SGNYPWKQSSFEGEWVIGSTAGGCRN 402

Query: 488 YLDTFWHNPQYVIRLDDPDEDDEEGNCTVIIALLQKNRRSRRNMGVECLTIGFAVYRVTE 547
           Y DTFWHNPQYV+ L +PD+DD EG  T IIALLQKNRRS+RN G++CLT+G  +YRVTE
Sbjct: 403 YPDTFWHNPQYVVHLKEPDKDDAEGKATAIIALLQKNRRSKRNKGMDCLTVGLIIYRVTE 462

Query: 548 RDLAQKPLKMNFFKYNASAARSPAFINLREVSCRFKLPPGTYVIVPSTFEPNEEGEFIIR 607
           RDL +KPL   FF  NAS ARS  F+NLREV+CRF++ PGTYV+VPSTFEPN EGEF+IR
Sbjct: 463 RDLIRKPLPKEFFLRNASIARS-TFVNLREVTCRFRMDPGTYVVVPSTFEPNVEGEFMIR 521

Query: 608 VFSETANSMMENDDNVGVGDLDDRIAPDVPGYVQPSPQRQAMERLFLDVAGADGEVDWVE 667
           VFSE  + M EN+D VG  DLD RI   VP   +P PQRQAME+LFLDVAG DGEVDW+E
Sbjct: 522 VFSECPDCMTENEDCVGECDLDPRIKMKVPDPTKPDPQRQAMEKLFLDVAGVDGEVDWME 581

Query: 668 LKRILDHSFRDD-NISSEGFSKD------------------VCRAMVAMLDVDHTGKLGF 708
           LK +LDH FRDD  I+++G S+                   VC  ++AML   +    G 
Sbjct: 582 LKLVLDHCFRDDIAIAAKGVSRSYHVAPVESKKSLTPQGEVVCCGLLAMLQDWYVNMAGG 641

Query: 709 EEFQQLLTD----IAKWKA-------------------VFKLYDTEGSGR---------- 735
           +   +  T     +AK +A                   +  + D + SG+          
Sbjct: 642 DNRPERSTSGDFVVAKERAPLMTAESSAVGFSKDACRSMVAMLDEDQSGKLGFLEFQKLL 701

Query: 736 --------------------LSPFQLREALNSAGYHLNNRILNALVHRYGSRSGTIPFDD 775
                               L+PF+LR AL SAGYHLN++ILN+L+HRYGSR G I FDD
Sbjct: 702 TEIARWKAVFKLYDTDRSGHLNPFELRAALQSAGYHLNSKILNSLMHRYGSREGEIWFDD 761

Query: 776 FIMCAVKIKTMIEIFRERDTDGTNQATFSMDEWVEKTLY 814
           FI CAVKIKTMI+IFR +D +G   A+F+MDEW++KT+Y
Sbjct: 762 FITCAVKIKTMIDIFRAKDVNGI--ASFNMDEWIQKTIY 798



==> gi|600420|emb|CAA86993.1| Calpain [Drosophila melanogaster]
          Length = 828

 Score =  853 bits (2205), Expect = 0.0
 Identities = 390/558 (69%), Positives = 462/558 (82%), Gaps = 1/558 (0%)

Query: 122 LGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFEDPEFPASASSLMYSKRPDRHYEWLRPHE 181
           LG++++      +VQD+  I   CL +G+LFEDP FPAS  SL +S+RPDRH EWLRPHE
Sbjct: 59  LGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHE 118

Query: 182 ICDGPEFFVEGFSRFDVQQGELGDCWLLAACANLTQDHKMFLRVVPEDNSFEDGYAGVFH 241
           I + P+FFVEG+SRFDVQQGELGDCWLLAA ANLTQ+  +F RV+P + SFE+ YAG+FH
Sbjct: 119 IAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFH 178

Query: 242 FRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSEQNEFWSALLEKAYAKLHGSYESLRGGTT 301
           FRFWQYGKWVDV+IDDRLPTY G+L+YM S+E+NEFWSALLEKAYAKLHGSYE+L+GG+T
Sbjct: 179 FRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGST 238

Query: 302 CEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKGFKRNSMFGCSIEADPHVLEAETPEGLIR 361
           CEAMEDFTGGV+E YDLK+  P NLF I++K  +RNSM GCSIE DP+V EAETP+GLIR
Sbjct: 239 CEAMEDFTGGVSEWYDLKE-APGNLFTILQKAAERNSMMGCSIEPDPNVTEAETPQGLIR 297

Query: 362 GHAYSITKIQLVDIETPGRSGKIPLIRLRNPWGNEAEWNGPWSDKSPEWRYIPDEQKQEL 421
           GHAYSITK+ L+DI TP R GKIP+IR+RNPWGNEAEWNGPWSD SPEWRYIP+EQK E+
Sbjct: 298 GHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEI 357

Query: 422 GLNFDHDGEFWMSYRDFTRYFDRMEICNLSPDSLSDDEMTRGKISWEMSMFEGEWAVGTT 481
           GL FD DGEFWMS++DF  +FDR+EICNLSPDSL++D+   GK  WEMSM+EGEW  G T
Sbjct: 358 GLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVT 417

Query: 482 AGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGNCTVIIALLQKNRRSRRNMGVECLTIGFA 541
           AGGCRN+LDTFWHNPQY+I L DPDE+DEEG CTVI+AL+QKNRRS+RNMG+ECLTIGFA
Sbjct: 418 AGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFA 477

Query: 542 VYRVTERDLAQKPLKMNFFKYNASAARSPAFINLREVSCRFKLPPGTYVIVPSTFEPNEE 601
           +Y + +R+L  +P  +NFF+Y +S  RSP FIN REV  RFKLPPG Y+IVPSTF+PNEE
Sbjct: 478 IYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEE 537

Query: 602 GEFIIRVFSETANSMMENDDNVGVGDLDDRIAPDVPGYVQPSPQRQAMERLFLDVAGADG 661
           GEFIIRVFSET N+M ENDD+VG G   D I P  P      PQ++ + RLF  +AG D 
Sbjct: 538 GEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKPIDPQKEGLRRLFDSIAGKDM 597

Query: 662 EVDWVELKRILDHSFRDD 679
           EVDW+ELKRILDHS RDD
Sbjct: 598 EVDWMELKRILDHSMRDD 615



 Score =  209 bits (533), Expect = 4e-052
 Identities = 96/133 (72%), Positives = 116/133 (87%)

Query: 683 SEGFSKDVCRAMVAMLDVDHTGKLGFEEFQQLLTDIAKWKAVFKLYDTEGSGRLSPFQLR 742
           + GFSKDVCR+MVAMLD D +GKLGFEEF+ LL++IAKWKA+FK+YD E +GR+S FQLR
Sbjct: 696 THGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLR 755

Query: 743 EALNSAGYHLNNRILNALVHRYGSRSGTIPFDDFIMCAVKIKTMIEIFRERDTDGTNQAT 802
           EALNSAGYHLNNR+LN L HRYGSR G I FDDFIMCAVKIKT I+IF+ERDT+    AT
Sbjct: 756 EALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETAT 815

Query: 803 FSMDEWVEKTLYS 815
           F+++EW+E+T+YS
Sbjct: 816 FTLEEWIERTIYS 828



==> gi|17137010|ref|NP_477047.1| Calpain-A CG7563-PB, isoform B
           [Drosophila melanogaster]
           (Calcium-activated neutral proteinase A) (CANP A)
           [Contains: Calpain A catalytic subunit]
           [Drosophila melanogaster] >gi|15291667|gb|AAK93102.1|
           LD22862p [Drosophila melanogaster]
          Length = 828

 Score =  853 bits (2205), Expect = 0.0
 Identities = 390/558 (69%), Positives = 462/558 (82%), Gaps = 1/558 (0%)

Query: 122 LGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFEDPEFPASASSLMYSKRPDRHYEWLRPHE 181
           LG++++      +VQD+  I   CL +G+LFEDP FPAS  SL +S+RPDRH EWLRPHE
Sbjct: 59  LGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHE 118

Query: 182 ICDGPEFFVEGFSRFDVQQGELGDCWLLAACANLTQDHKMFLRVVPEDNSFEDGYAGVFH 241
           I + P+FFVEG+SRFDVQQGELGDCWLLAA ANLTQ+  +F RV+P + SFE+ YAG+FH
Sbjct: 119 IAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFH 178

Query: 242 FRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSEQNEFWSALLEKAYAKLHGSYESLRGGTT 301
           FRFWQYGKWVDV+IDDRLPTY G+L+YM S+E+NEFWSALLEKAYAKLHGSYE+L+GG+T
Sbjct: 179 FRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGST 238

Query: 302 CEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKGFKRNSMFGCSIEADPHVLEAETPEGLIR 361
           CEAMEDFTGGV+E YDLK+  P NLF I++K  +RNSM GCSIE DP+V EAETP+GLIR
Sbjct: 239 CEAMEDFTGGVSEWYDLKE-APGNLFTILQKAAERNSMMGCSIEPDPNVTEAETPQGLIR 297

Query: 362 GHAYSITKIQLVDIETPGRSGKIPLIRLRNPWGNEAEWNGPWSDKSPEWRYIPDEQKQEL 421
           GHAYSITK+ L+DI TP R GKIP+IR+RNPWGNEAEWNGPWSD SPEWRYIP+EQK E+
Sbjct: 298 GHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEI 357

Query: 422 GLNFDHDGEFWMSYRDFTRYFDRMEICNLSPDSLSDDEMTRGKISWEMSMFEGEWAVGTT 481
           GL FD DGEFWMS++DF  +FDR+EICNLSPDSL++D+   GK  WEMSM+EGEW  G T
Sbjct: 358 GLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVT 417

Query: 482 AGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGNCTVIIALLQKNRRSRRNMGVECLTIGFA 541
           AGGCRN+LDTFWHNPQY+I L DPDE+DEEG CTVI+AL+QKNRRS+RNMG+ECLTIGFA
Sbjct: 418 AGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFA 477

Query: 542 VYRVTERDLAQKPLKMNFFKYNASAARSPAFINLREVSCRFKLPPGTYVIVPSTFEPNEE 601
           +Y + +R+L  +P  +NFF+Y +S  RSP FIN REV  RFKLPPG Y+IVPSTF+PNEE
Sbjct: 478 IYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEE 537

Query: 602 GEFIIRVFSETANSMMENDDNVGVGDLDDRIAPDVPGYVQPSPQRQAMERLFLDVAGADG 661
           GEFIIRVFSET N+M ENDD+VG G   D I P  P      PQ++ + RLF  +AG D 
Sbjct: 538 GEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKPIDPQKEGLRRLFDSIAGKDM 597

Query: 662 EVDWVELKRILDHSFRDD 679
           EVDW+ELKRILDHS RDD
Sbjct: 598 EVDWMELKRILDHSMRDD 615



 Score =  209 bits (533), Expect = 4e-052
 Identities = 96/133 (72%), Positives = 116/133 (87%)

Query: 683 SEGFSKDVCRAMVAMLDVDHTGKLGFEEFQQLLTDIAKWKAVFKLYDTEGSGRLSPFQLR 742
           + GFSKDVCR+MVAMLD D +GKLGFEEF+ LL++IAKWKA+FK+YD E +GR+S FQLR
Sbjct: 696 THGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLR 755

Query: 743 EALNSAGYHLNNRILNALVHRYGSRSGTIPFDDFIMCAVKIKTMIEIFRERDTDGTNQAT 802
           EALNSAGYHLNNR+LN L HRYGSR G I FDDFIMCAVKIKT I+IF+ERDT+    AT
Sbjct: 756 EALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETAT 815

Query: 803 FSMDEWVEKTLYS 815
           F+++EW+E+T+YS
Sbjct: 816 FTLEEWIERTIYS 828



==> gi|562289|emb|CAA55298.1| calpain [Drosophila melanogaster]
          Length = 828

 Score =  853 bits (2203), Expect = 0.0
 Identities = 390/558 (69%), Positives = 462/558 (82%), Gaps = 1/558 (0%)

Query: 122 LGDRNAGQRSSFDVQDFYQIRQQCLDNGTLFEDPEFPASASSLMYSKRPDRHYEWLRPHE 181
           LG++++      +VQD+  I   CL +G+LFEDP FPAS  SL +S+RPDRH EWLRPHE
Sbjct: 59  LGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHE 118

Query: 182 ICDGPEFFVEGFSRFDVQQGELGDCWLLAACANLTQDHKMFLRVVPEDNSFEDGYAGVFH 241
           I + P+FFVEG+SRFDVQQGELGDCWLLAA ANLTQ+  +F RV+P + SFE+ YAG+FH
Sbjct: 119 IAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFH 178

Query: 242 FRFWQYGKWVDVVIDDRLPTYRGQLIYMRSSEQNEFWSALLEKAYAKLHGSYESLRGGTT 301
           FRFWQYGKWVDV+IDDRLPTY G+L+YM S+E+NEFWSALLEKAYAKLHGSYE+L+GG+T
Sbjct: 179 FRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGST 238

Query: 302 CEAMEDFTGGVAEMYDLKDQTPPNLFEIIEKGFKRNSMFGCSIEADPHVLEAETPEGLIR 361
           CEAMEDFTGGV+E YDLK+  P NLF I++K  +RNSM GCSIE DP+V EAETP+GLIR
Sbjct: 239 CEAMEDFTGGVSEWYDLKE-APGNLFTILQKAAERNSMMGCSIEPDPNVTEAETPQGLIR 297

Query: 362 GHAYSITKIQLVDIETPGRSGKIPLIRLRNPWGNEAEWNGPWSDKSPEWRYIPDEQKQEL 421
           GHAYSITK+ L+DI TP R GKIP+IR+RNPWGNEAEWNGPWSD SPEWRYIP+EQK E+
Sbjct: 298 GHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEI 357

Query: 422 GLNFDHDGEFWMSYRDFTRYFDRMEICNLSPDSLSDDEMTRGKISWEMSMFEGEWAVGTT 481
           GL FD DGEFWMS++DF  +FDR+EICNLSPDSL++D+   GK  WEMSM+EGEW  G T
Sbjct: 358 GLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSGKRKWEMSMYEGEWTPGVT 417

Query: 482 AGGCRNYLDTFWHNPQYVIRLDDPDEDDEEGNCTVIIALLQKNRRSRRNMGVECLTIGFA 541
           AGGCRN+LDTFWHNPQY+I L DPDE+DEEG CTVI+AL+QKNRRS+RNMG+ECLTIGFA
Sbjct: 418 AGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFA 477

Query: 542 VYRVTERDLAQKPLKMNFFKYNASAARSPAFINLREVSCRFKLPPGTYVIVPSTFEPNEE 601
           +Y + +R+L  +P  +NFF+Y +S  RSP FIN REV  RFKLPPG Y+IVPSTF+PNEE
Sbjct: 478 IYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEE 537

Query: 602 GEFIIRVFSETANSMMENDDNVGVGDLDDRIAPDVPGYVQPSPQRQAMERLFLDVAGADG 661
           GEFIIRVFSET N+M ENDD+VG G   D I P  P      PQ++ + RLF  +AG D 
Sbjct: 538 GEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKPIDPQKEGLRRLFDSIAGKDM 597

Query: 662 EVDWVELKRILDHSFRDD 679
           EVDW+ELKRILDHS RDD
Sbjct: 598 EVDWMELKRILDHSMRDD 615



 Score =  209 bits (533), Expect = 4e-052
 Identities = 96/133 (72%), Positives = 116/133 (87%)

Query: 683 SEGFSKDVCRAMVAMLDVDHTGKLGFEEFQQLLTDIAKWKAVFKLYDTEGSGRLSPFQLR 742
           + GFSKDVCR+MVAMLD D +GKLGFEEF+ LL++IAKWKA+FK+YD E +GR+S FQLR
Sbjct: 696 THGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLR 755

Query: 743 EALNSAGYHLNNRILNALVHRYGSRSGTIPFDDFIMCAVKIKTMIEIFRERDTDGTNQAT 802
           EALNSAGYHLNNR+LN L HRYGSR G I FDDFIMCAVKIKT I+IF+ERDT+    AT
Sbjct: 756 EALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETAT 815

Query: 803 FSMDEWVEKTLYS 815
           F+++EW+E+T+YS
Sbjct: 816 FTLEEWIERTIYS 828