>AGAP007293-PA

gnl|CDD|64515 pfam00653, BIR, Inhibitor of Apoptosis domain. BIR...    91   1e-019
gnl|CDD|64456 pfam00591, Glycos_transf_3, Glycosyl transferase f...    30   0.24 
gnl|CDD|71404 pfam07967, zf-C3HC, C3HC zinc finger-like. This zi...    28   0.75 


==> gnl|CDD|64515 pfam00653, BIR, Inhibitor of Apoptosis domain. BIR stands for
           'Baculovirus Inhibitor of apoptosis protein Repeat'. It
           is found repeated in inhibitor of apoptosis proteins
           (IAPs), and in fact it is also known as IAP repeat.
           These domains characteristically have a number of
           invariant residues, including 3 conserved cysteines and
           one conserved histidine that coordinate a zinc ion. They
           are usually made up of 4-5 alpha helices and a
           three-stranded beta-sheet. BIR is also found in other
           proteins known as BIR-domain-containing proteins
           (BIRPs), such as Survivin..
          Length = 66

 Score = 91.1 bits (226), Expect = 1e-019
 Identities = 34/66 (51%), Positives = 43/66 (65%)

Query: 181 RLATFKEWPKSIPQTPTQMADAGFFYTGKSDVVACYYCGGNLRDWLAEDDPWVEHVRNFS 240
           RL TF+ WP S  Q P Q+A AGF+YTG  D V C++CG  L++W   DDPW EH R   
Sbjct: 1   RLRTFQNWPISNLQFPEQLAKAGFYYTGVGDEVRCFFCGVELKNWEPGDDPWEEHARWSP 60

Query: 241 ECPYVK 246
            CP+V+
Sbjct: 61  NCPFVR 66



 Score = 71.1 bits (174), Expect = 1e-013
 Identities = 32/65 (49%), Positives = 43/65 (66%), Gaps = 1/65 (1%)

Query: 33 RLRTFPLWTVP-YIYPEELARWGFFYTGYRDCVRCYFCRIELGGWDEHDVVIEEHLKWSP 91
          RLRTF  W +    +PE+LA+ GF+YTG  D VRC+FC +EL  W+  D   EEH +WSP
Sbjct: 1  RLRTFQNWPISNLQFPEQLAKAGFYYTGVGDEVRCFFCGVELKNWEPGDDPWEEHARWSP 60

Query: 92 HCRLM 96
          +C  +
Sbjct: 61 NCPFV 65



==> gnl|CDD|64456 pfam00591, Glycos_transf_3, Glycosyl transferase family, a/b
           domain. This family includes anthranilate
           phosphoribosyltransferase (TrpD), thymidine
           phosphorylase. All these proteins can transfer a
           phosphorylated ribose substrate..
          Length = 254

 Score = 29.8 bits (67), Expect = 0.24
 Identities = 14/36 (38%), Positives = 15/36 (41%), Gaps = 9/36 (25%)

Query: 120 DTTGTG---------STSAWSAAATAAVAVAMESNR 146
           D  GTG         ST+A   AA   V VA   NR
Sbjct: 6   DIVGTGGDGDNTFNISTAAAFVAAACGVKVAKHGNR 41



==> gnl|CDD|71404 pfam07967, zf-C3HC, C3HC zinc finger-like. This zinc-finger like
           domain is distributed throughout the eukaryotic kingdom
           in NIPA (Nuclear interacting partner of ALK) proteins.
           NIPA is implicate to perform some sort of antiapoptotic
           role in nucleophosmin-anaplastic lymphoma kinase (ALK)
           mediated signaling events. The domain is often repeated,
           with the second domain usually containing a large insert
           (approximately 90 residues) after the first three
           cysteine residues. The Schizosaccharomyces pombe the
           protein containing this domain is involved in mRNA
           export from the nucleus..
          Length = 132

 Score = 28.4 bits (63), Expect = 0.75
 Identities = 21/74 (28%), Positives = 27/74 (36%), Gaps = 4/74 (5%)

Query: 180 DRLATFKE-WPKSIPQT--PTQMADAGFFYTGKSDVVACYYCGGNLRDWLAEDDPWVEHV 236
            RLATFK       P    P   A  G+    K D++ C  CG  L   L      V+ V
Sbjct: 9   RRLATFKSLTWFGKPSAVSPVNCAKRGWVCVSK-DMLKCVSCGAYLCVSLPNVLDEVKEV 67

Query: 237 RNFSECPYVKLVKT 250
                    K ++T
Sbjct: 68  YEKRGEKLAKQLET 81