>AGAP001864-PA

Q27589|CP4D2_DROME Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2) -...   357   9e-098
O46051|C4D14_DROME Probable cytochrome P450 4d14 (EC 1.14.-.-) (...   355   2e-097
P29981|CP4C1_BLADI Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1) ...   341   4e-093
Q9DBW0|CP4V3_MOUSE Cytochrome P450 4V3 (EC 1.14.-.-) - Mus muscu...   331   5e-090
Q5RCN6|CP4V2_PONPY Cytochrome P450 4V2 (EC 1.14.-.-) - Pongo pyg...   331   5e-090
Q6ZWL3|CP4V2_HUMAN Cytochrome P450 4V2 (EC 1.14.-.-) - Homo sapi...   330   7e-090
Q9VLZ7|C4D21_DROME Probable cytochrome P450 4d21 (EC 1.14.-.-) (...   329   2e-089
Q9W011|C4D20_DROME Probable cytochrome P450 4d20 (EC 1.14.-.-) (...   327   6e-089
Q9VA27|CP4C3_DROME Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3) -...   327   1e-088
Q9VXY0|CP4S3_DROME Probable cytochrome P450 4s3 (EC 1.14.-.-) (C...   322   3e-087


==> Q27589|CP4D2_DROME Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2) -
           Drosophila melanogaster (Fruit fly)
          Length = 501

 Score =  357 bits (915), Expect = 9e-098
 Identities = 204/491 (41%), Positives = 301/491 (61%), Gaps = 31/491 (6%)

Query: 48  IPVLGSAYLFKDPTPEGIFQTFTGFHRQFGRNLITQSLFNFPSMQVCDPKVIEQIMQART 107
           +P LG+  +++   PE I        R++GR L    + +  ++   DP+ IE ++ ++ 
Sbjct: 37  LPFLGNLLMYRGLDPEQIMDFVKKNQRKYGR-LYRVWILHQLAVFSTDPRDIEFVLSSQQ 95

Query: 108 -IEKTIIYDFMVPWLGTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEK 166
            I K  +Y  +  WLG GL++STG KW  RRKIITPTFHFKILE F+ I + Q+ V++E+
Sbjct: 96  HITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQ 155

Query: 167 LKQNANS-TDFDIYEHVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRLF 225
           L+  A+  T  +I+  +   ALDII+E+AMG K+N Q+ PN  YV AV ++++I++KR  
Sbjct: 156 LQSRADGKTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFI 215

Query: 226 SFLREYKWAFQFTK--SHRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEED 283
              +   W F+ T+    +RQ++ +K++HDF  N+I ER++ L +  ++   +E   E +
Sbjct: 216 HAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEE---EVN 272

Query: 284 VYGKRRMTLLDLLLNLEEEDVYGKRRMTLLDLLLNVTIDGKPLSDSDIREEVDTFMFAGH 343
             G+                   KRRM LLD+LL  TIDG PLSD DIREEVDTFMF GH
Sbjct: 273 FLGQ-------------------KRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGH 313

Query: 344 DTTTSCISFAAYYLSRDATVQQRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETL 403
           DTTTS ISF  Y +SR   VQQR+  EI  ++G D K+  +T   L ELK+++ VIKE+L
Sbjct: 314 DTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKS-PVTLRDLGELKFMENVIKESL 372

Query: 404 RINPSVPIIGRRSAGDMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEAS 463
           R++P VP+IGR  A D+ I G  IP G +F + I+ L  DPE +  P  F PERF  +  
Sbjct: 373 RLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVP 432

Query: 464 EKRQPYSYIPFSVGARNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKLRIKTDMTLKP 523
           +   PY+YIPFS G RNCIGQ++AMLE+K+ + KL+ +++LLP     + R   ++ L+ 
Sbjct: 433 Q-IHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGP--EPRHSMNIVLRS 489

Query: 524 VDGAFIKIVPR 534
            +G  + + PR
Sbjct: 490 ANGVHLGLKPR 500



==> O46051|C4D14_DROME Probable cytochrome P450 4d14 (EC 1.14.-.-)
           (CYPIVD14) - Drosophila melanogaster (Fruit fly)
          Length = 507

 Score =  355 bits (912), Expect = 2e-097
 Identities = 203/465 (43%), Positives = 288/465 (61%), Gaps = 26/465 (5%)

Query: 49  PVLGSAYLFKDPTPEGIFQTFTGFHRQFGRNLITQSLFNFPSMQVCDPKVIEQIMQAR-T 107
           P++G+A L  + +P+ IF        +FG+N+ TQ L     M   D K+IE IM ++ T
Sbjct: 40  PLVGNAPLLINESPKTIFDMQFRLIAEFGKNIKTQMLGESGFM-TADSKMIEAIMSSQQT 98

Query: 108 IEKTIIYDFMVPWLGTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKL 167
           I+K  +Y  +V WLG GL++S G KW +RRKIITP FHFKILEDF+ + + Q+  +++KL
Sbjct: 99  IQKNNLYSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKL 158

Query: 168 KQNANS-TDFDIYEHVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRLFS 226
              A+  T  +++     CA+DII+E+AMGVK+N Q QP   YV +V   S ++ +R  +
Sbjct: 159 YDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMN 218

Query: 227 FLREYKWAFQ--FTKSHRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDV 284
            L+   +  +  + K   +  + VK +HDF ++VI+ER++ LQ                 
Sbjct: 219 PLQRLDFTMKLFYPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADG----------- 267

Query: 285 YGKRRMTLLDLLLNLEEEDVYGKRRMTLLDLLLNVTIDGKPLSDSDIREEVDTFMFAGHD 344
            G     LL+        DV  KRRM LLD+LL  TIDG PLS+ DIREEVDTFMF GHD
Sbjct: 268 -GDADAALLN--------DVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHD 318

Query: 345 TTTSCISFAAYYLSRDATVQQRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETLR 404
           TTTS I+F  Y L+R   VQ RV+ E+  ++G D K+  +T   L ELKYL+ VIKE+LR
Sbjct: 319 TTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDD-KSAPVTMKLLGELKYLECVIKESLR 377

Query: 405 INPSVPIIGRRSAGDMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEASE 464
           + PSVPIIGR  + D ++DG  IP   +  ILIY    DP+ +P+P +F P+RFS E   
Sbjct: 378 LFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKG 437

Query: 465 KRQPYSYIPFSVGARNCIGQRYAMLEIKTMLVKLVANYQLLPCDE 509
           +  P++Y PFS G RNCIGQ++AMLE+K+ + K+V +++LLP  E
Sbjct: 438 EISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGE 482



==> P29981|CP4C1_BLADI Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1) -
           Blaberus discoidalis (Tropical cockroach)
          Length = 511

 Score =  341 bits (875), Expect = 4e-093
 Identities = 201/537 (37%), Positives = 307/537 (57%), Gaps = 37/537 (6%)

Query: 3   IKMFLVLLTTLLGIAVTCMVVTIIRNRATVAKLKKQLHNFTVIPAIPVLGSAYLFKDPTP 62
           ++   +LL+T L I     +      RA    L  +L   T   A PV+G+A     P  
Sbjct: 1   MEFITILLSTALFIVTFLFLFRQGAKRARFVYLVNKLPGPT---AYPVVGNAIEAIVPRN 57

Query: 63  EGIFQTFTGFHRQFGRNLITQSLFNFPSMQV--CDPKVIEQIMQ-ARTIEKTIIYDFMVP 119
           + +FQ F    + +G       ++  P  QV    P+ +E I++  + I+K+++Y F+ P
Sbjct: 58  K-LFQVFDRRAKLYGP---LYRIWAGPIAQVGLTRPEHVELILRDTKHIDKSLVYSFIRP 113

Query: 120 WLGTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKLKQNANSTDFDIY 179
           WLG GL+  TG KW   RK+ITPTFHFKIL+ F+ +   ++++L++KL+      DFDIY
Sbjct: 114 WLGEGLLTGTGAKWHSHRKMITPTFHFKILDIFVDVFVEKSEILVKKLQSKVGGKDFDIY 173

Query: 180 EHVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRLFSFLREYKWAFQFTK 239
             +T+CALDII E+AMG+++N Q++  SEYV AV EIS++ ++R        K  F  T 
Sbjct: 174 PFITHCALDIICETAMGIQMNAQEESESEYVKAVYEISELTMQRSVRPWLHPKVIFDLTT 233

Query: 240 SHRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDVYGKRRMTLLDLLLNL 299
             +R  E ++I+H F + VI ERK                        R+MT +   ++ 
Sbjct: 234 MGKRYAECLRILHGFTNKVIQERK----------------------SLRQMTGMKPTISN 271

Query: 300 EEEDVYG-KRRMTLLDLLLNVTIDGKPLSDSDIREEVDTFMFAGHDTTTSCISFAAYYLS 358
           EE+++ G K+R+  LDLLL  + +G  +SD+DIREEVDTFMF GHDTT++ I +A + L 
Sbjct: 272 EEDELLGKKKRLAFLDLLLEASENGTKMSDTDIREEVDTFMFEGHDTTSAGICWALFLLG 331

Query: 359 RDATVQQRVYDEILAIV-GPDAKTQELTYGTLQELKYLDMVIKETLRINPSVPIIGRRSA 417
               +Q +VY+E+  I  G D  T   T   L ++KYL+ VIKE+LR+ PSVP IGR   
Sbjct: 332 SHPEIQDKVYEELDHIFQGSDRST---TMRDLADMKYLERVIKESLRLFPSVPFIGRVLK 388

Query: 418 GDMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEASEKRQPYSYIPFSVG 477
            D  I    +P G    + IY +H + + YP P  F+P+ F  E   KR PY+Y+PFS G
Sbjct: 389 EDTKIGDYLVPAGCMMNLQIYHVHRNQDQYPNPEAFNPDNFLPERVAKRHPYAYVPFSAG 448

Query: 478 ARNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKLRIKTDMTLKPVDGAFIKIVPR 534
            RNCIGQ++A LE KT+L  ++ N+++   ++R  L +  ++ L+P  G  ++++PR
Sbjct: 449 PRNCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMNELILRPESGIKVELIPR 505



==> Q9DBW0|CP4V3_MOUSE Cytochrome P450 4V3 (EC 1.14.-.-) - Mus musculus
           (Mouse)
          Length = 525

 Score =  331 bits (848), Expect = 5e-090
 Identities = 200/536 (37%), Positives = 308/536 (57%), Gaps = 32/536 (5%)

Query: 4   KMFLVLLTTLLGIAVTCMVVTIIRNRATVAKLKKQLHNF-TVIPAIPVLGSAYLFKDPTP 62
           K+ L    + + +A   ++++I     + A+  +Q+ +  +V  A P++G A L+  P  
Sbjct: 12  KLLLWGAASAVSLAGATILISIFPMLVSYARKWQQMRSIPSVARAYPLVGHA-LYMKPNN 70

Query: 63  EGIFQTFTGFHRQFGR-NLITQSLFNFPSMQVCDPKVIEQIM-QARTIEKTIIYDFMVPW 120
              FQ    +  +F    +I   +   P + +   + +E I+  ++ I+K+ +Y F+ PW
Sbjct: 71  AEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPW 130

Query: 121 LGTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKLKQNANSTDFDIYE 180
           LG GL+ STG+KW  RRK++TPTFHF ILE+FL +MN Q ++L+ KL+++ N   F+ + 
Sbjct: 131 LGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAFNCFF 190

Query: 181 HVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRL-FSFLREYKWAFQFTK 239
           ++T CALDII E+AMG  +  Q   +SEYV  V  +SD+I +R+   +L    W   F K
Sbjct: 191 YITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVF-K 249

Query: 240 SHRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDVYGKRRMTLLDLLLNL 299
             R  +  +K +H F +NVI+ER K            E+  EED  G  R  +       
Sbjct: 250 EGRDHKRGLKCLHTFTNNVIAERVK------------ERKAEEDWTGAGRGPIPSK---- 293

Query: 300 EEEDVYGKRRMTLLDLLLNVTID-GKPLSDSDIREEVDTFMFAGHDTTTSCISFAAYYLS 358
                   +R   LDLLL+VT + G  LS  DIREEVDTFMF GHDTT + I+++ Y L 
Sbjct: 294 -------NKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLG 346

Query: 359 RDATVQQRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETLRINPSVPIIGRRSAG 418
            +  VQ++V  E+  + G   +   +T   L++LKYLD VIKETLR+ PSVP+  R  + 
Sbjct: 347 TNPEVQRKVDQELDEVFGRSHRP--VTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSE 404

Query: 419 DMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEASEKRQPYSYIPFSVGA 478
           D  + G  + KG +  I+ YALH DP  +P+P  F PERF  E S+ R PY+Y+PFS G 
Sbjct: 405 DCEVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQGRHPYAYVPFSAGP 464

Query: 479 RNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKLRIKTDMTLKPVDGAFIKIVPR 534
           RNCIGQ++A++E KT+L  ++  + +    +R +L +  D+ L+P +G +IK+  R
Sbjct: 465 RNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLILRPNNGIWIKLKRR 520



==> Q5RCN6|CP4V2_PONPY Cytochrome P450 4V2 (EC 1.14.-.-) - Pongo
           pygmaeus (Orangutan)
          Length = 525

 Score =  331 bits (848), Expect = 5e-090
 Identities = 201/536 (37%), Positives = 310/536 (57%), Gaps = 32/536 (5%)

Query: 4   KMFLVLLTTLLGIAVTCMVVTIIRNRATVAKLKKQLHNF-TVIPAIPVLGSAYLFKDPTP 62
           K+ L    + + +A   +V+++++  A+ A+  +Q+    TV  A P++G A L K    
Sbjct: 12  KLLLWGAASAVSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALLMKRDGR 71

Query: 63  EGIFQTFTGFHRQFGRN-LITQSLFNFPSMQVCDPKVIEQIM-QARTIEKTIIYDFMVPW 120
           E  FQ    +  ++    L+   +   P + + + + +E I+  +R I+K+ +Y F+ PW
Sbjct: 72  E-FFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSRQIDKSSMYKFLEPW 130

Query: 121 LGTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKLKQNANSTDFDIYE 180
           LG GL+ STG KW  RRK++TPTFHF ILEDFL IMN Q ++L++KL+++ N   F+ + 
Sbjct: 131 LGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHVNQEAFNCFF 190

Query: 181 HVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRL-FSFLREYKWAFQFTK 239
           ++T CALDII E+AMG  +  Q   +SEYV AV  +S +I +R+   +L    W   F K
Sbjct: 191 YITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSQMIFQRIKMPWLWLDLWYLMF-K 249

Query: 240 SHRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDVYGKRRMTLLDLLLNL 299
                E+ +KI+H F +NVI+ER  ++              +ED  G  R +        
Sbjct: 250 EGWEHEKGLKILHTFTNNVIAERANEMN------------ADEDCRGVGRGSAPS----- 292

Query: 300 EEEDVYGKRRMTLLDLLLNVTID-GKPLSDSDIREEVDTFMFAGHDTTTSCISFAAYYLS 358
                   +R   LDLLL+VT D G  LS  DIREEVDTFMF GHDTT + I+++ Y L 
Sbjct: 293 ------KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLG 346

Query: 359 RDATVQQRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETLRINPSVPIIGRRSAG 418
            +  VQQ+V  E+  + G     +  T   L++L+YL+ VIKETLR+ PSVP+  R  + 
Sbjct: 347 CNPEVQQKVDHELDDVFG--KSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSE 404

Query: 419 DMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEASEKRQPYSYIPFSVGA 478
           D  + G  + KG +  I+ YALH DP  +P P  F PERF  E ++ R PY+Y+PFS G 
Sbjct: 405 DCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGP 464

Query: 479 RNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKLRIKTDMTLKPVDGAFIKIVPR 534
           RNCIGQ++A++E KT+L  ++ ++ +    +R +L ++  + L+P +G +IK+  R
Sbjct: 465 RNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520



==> Q6ZWL3|CP4V2_HUMAN Cytochrome P450 4V2 (EC 1.14.-.-) - Homo sapiens
           (Human)
          Length = 525

 Score =  330 bits (847), Expect = 7e-090
 Identities = 198/536 (36%), Positives = 310/536 (57%), Gaps = 32/536 (5%)

Query: 4   KMFLVLLTTLLGIAVTCMVVTIIRNRATVAKLKKQLHNF-TVIPAIPVLGSAYLFKDPTP 62
           K+ L    + L +A   +V+++++  A+ A+  +Q+    TV  A P++G A L K P  
Sbjct: 12  KLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALLMK-PDG 70

Query: 63  EGIFQTFTGFHRQFGRN-LITQSLFNFPSMQVCDPKVIEQIM-QARTIEKTIIYDFMVPW 120
              FQ    +  ++    L+   +   P + + + + +E I+  ++ I+K+ +Y F+ PW
Sbjct: 71  REFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPW 130

Query: 121 LGTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKLKQNANSTDFDIYE 180
           LG GL+ STG KW  RRK++TPTFHF ILEDFL IMN Q ++L++KL+++ N   F+ + 
Sbjct: 131 LGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFF 190

Query: 181 HVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRL-FSFLREYKWAFQFTK 239
           ++T CALDII E+AMG  +  Q   +SEYV AV  +S++I +R+   +L    W   F +
Sbjct: 191 YITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKE 250

Query: 240 SHRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDVYGKRRMTLLDLLLNL 299
               ++ L KI+H F ++VI+ER  ++               ED  G  R +        
Sbjct: 251 GWEHKKSL-KILHTFTNSVIAERANEMN------------ANEDCRGDGRGSAPS----- 292

Query: 300 EEEDVYGKRRMTLLDLLLNVTID-GKPLSDSDIREEVDTFMFAGHDTTTSCISFAAYYLS 358
                   +R   LDLLL+VT D G  LS  DIREEVDTFMF GHDTT + I+++ Y L 
Sbjct: 293 ------KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLG 346

Query: 359 RDATVQQRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETLRINPSVPIIGRRSAG 418
            +  VQ++V  E+  + G     +  T   L++L+YL+ VIKETLR+ PSVP+  R  + 
Sbjct: 347 SNPEVQKKVDHELDDVFG--KSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSE 404

Query: 419 DMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEASEKRQPYSYIPFSVGA 478
           D  + G  + KG +  I+ YALH DP  +P P  F PERF  E ++ R PY+Y+PFS G 
Sbjct: 405 DCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGP 464

Query: 479 RNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKLRIKTDMTLKPVDGAFIKIVPR 534
           RNCIGQ++A++E KT+L  ++ ++ +    +R +L ++  + L+P +G +IK+  R
Sbjct: 465 RNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520



==> Q9VLZ7|C4D21_DROME Probable cytochrome P450 4d21 (EC 1.14.-.-)
           (CYPIVD21) - Drosophila melanogaster (Fruit fly)
          Length = 511

 Score =  329 bits (844), Expect = 2e-089
 Identities = 194/503 (38%), Positives = 292/503 (58%), Gaps = 34/503 (6%)

Query: 13  LLGIAVTCMVVTIIRNR----ATVAKLKKQLHNFTVIPAIPVLGSAYLFKDPTPEGIFQT 68
           LLGIAV  M +    +R        +  + L  FT    IP++G+        PE   Q 
Sbjct: 4   LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFT----IPIVGNGLQALTLRPENFIQR 59

Query: 69  FTGFHRQFGRNLITQSLFNFPSMQVCDPKVIEQIMQARTI-EKTIIYDFMVPWLGTGLVV 127
           F  +  ++G+      L     +   D K  E I+ + T+ +K  +Y F+  +LG GL++
Sbjct: 60  FGDYFNKYGKTFRLWILGEC-LIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLL 118

Query: 128 STGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKLKQNANS-TDFDIYEHVTYCA 186
           STG KW  RRK++ P FHFK LE+F+ IM+  + +++EKLK  A+  T  D+++ V+  A
Sbjct: 119 STGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEA 178

Query: 187 LDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRLFSFLREYKWAFQFTKS--HRRQ 244
           LD+ +E+AMGV++N Q +PN  Y  A+K +  I  KRL S    Y W F       +RR 
Sbjct: 179 LDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRL 238

Query: 245 EELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDVYGKRRMTLLDLLLNLEEEDV 304
           ++ + I+ DF   VI ER+  L          E+   +  Y           L + ++D+
Sbjct: 239 QKDIAIMQDFTDKVIRERRAIL----------ERARADGTYKP---------LIMGDDDI 279

Query: 305 YGKRRMTLLDLLLNVTIDGKPLSDSDIREEVDTFMFAGHDTTTSCISFAAYYLSRDATVQ 364
            GK +MTLLD+LL  TID KPLSD DIREEVD F+FAG DTTTS +S A + +SR   VQ
Sbjct: 280 GGKAKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQ 339

Query: 365 QRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETLRINPSVPIIGRRSAGDMLIDG 424
           + +Y+E+++++GPD     +T   L ELKYLD VIKET+R++P VPI+GR    D+ I  
Sbjct: 340 ECIYEELVSVLGPDPDA-SVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGE 398

Query: 425 VTIPKGMDFGILIYALHNDPELYPEPARFDPERFSE-EASEKRQPYSYIPFSVGARNCIG 483
           +TIP      ++ Y ++ DPE +P+P  F PER+ + + +    P +YIPFS G +NCIG
Sbjct: 399 ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIG 458

Query: 484 QRYAMLEIKTMLVKLVANYQLLP 506
           Q++A L++K ++ K++ +Y+LLP
Sbjct: 459 QKFANLQMKALISKVIRHYELLP 481



==> Q9W011|C4D20_DROME Probable cytochrome P450 4d20 (EC 1.14.-.-)
           (CYPIVD20) - Drosophila melanogaster (Fruit fly)
          Length = 510

 Score =  327 bits (839), Expect = 6e-089
 Identities = 193/536 (36%), Positives = 304/536 (56%), Gaps = 43/536 (8%)

Query: 10  LTTLLGIAVTCMVVTIIRNRATVAKLKKQLHNFTVIP---AIPVLGSAYLFKDPTPEGIF 66
           LT + G  +  +     R R  V   +K     + IP   +IP+LG          E I 
Sbjct: 3   LTLITGALILLLTWDFGRKRQRVLAFEK-----SAIPGPISIPILGCGLQALHLGAENII 57

Query: 67  ----QTFTGFHRQFGRNLITQSLFNFPSMQVCDPKVIEQIMQARTI-EKTIIYDFMVPWL 121
               + F  + + F   ++ +SL     +Q       E I+ + T+ EK  +Y+++ P+L
Sbjct: 58  GWVGEKFDKYGKTFRFWILGESLIYTKDLQY-----FETILSSTTLLEKGQLYEYLRPFL 112

Query: 122 GTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKLKQNANS-TDFDIYE 180
             GL+VSTG KW  RRKI T  FHFK+LE ++ IM+  + V+++ L++ A+  T  D+ +
Sbjct: 113 NDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLK 172

Query: 181 HVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRLFSFLREYKWAFQFTKS 240
           +V+  ALD+I+E+AMGV++N Q  P+  Y+ A+K +  I   R+F F R Y W F     
Sbjct: 173 YVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAP 232

Query: 241 --HRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDVYGKRRMTLLDLLLN 298
             HR+    ++++HDF   VISER++          T  + + +  Y           L+
Sbjct: 233 LLHRQLLSDIRVMHDFTDKVISERRE----------TVRRAKADGTYRP---------LS 273

Query: 299 LEEEDVYGKRRMTLLDLLLNVTIDGKPLSDSDIREEVDTFMFAGHDTTTSCISFAAYYLS 358
           L + ++  K +M LLD+LL  +I+ +PLSD+DIREEVDTFMF G DTT+S +S A Y ++
Sbjct: 274 LGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIA 333

Query: 359 RDATVQQRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETLRINPSVPIIGRRSAG 418
           R   VQQR+++E+  ++GPDA    +T   LQ+LKYLD VIKET+R+ P VP IGR +  
Sbjct: 334 RHPEVQQRIFEELQRVLGPDASAP-VTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQK 392

Query: 419 DMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEASEKRQPYSYIPFSVGA 478
           ++ I   TIP      +++Y  H D   +P+P  F PERF E+  +    ++Y+PFS G 
Sbjct: 393 ELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGP 452

Query: 479 RNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKLRIKTDMTLKPVDGAFIKIVPR 534
           +NCIGQ++A+LE+K ++ K++  Y+LLP  E  +L+   +  L+   G  + + PR
Sbjct: 453 KNCIGQKFAVLEMKVLISKVLRFYELLPLGE--ELKPMLNFILRSASGINVGLRPR 506



==> Q9VA27|CP4C3_DROME Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3) -
           Drosophila melanogaster (Fruit fly)
          Length = 535

 Score =  327 bits (837), Expect = 1e-088
 Identities = 189/536 (35%), Positives = 294/536 (54%), Gaps = 26/536 (4%)

Query: 2   VIKMFLVLLTTLLGIAVTCMVVTIIRNRATVAKLKKQLHNFTVIPAIPVLGSAYLFKDPT 61
           VI  +  +   LLG  +  +VV   R     ++L K +       A+P LG+A       
Sbjct: 22  VISGYSPITVFLLGSILIFLVVYNKRR----SRLVKYIEKIPGPAAMPFLGNAIEMNVDH 77

Query: 62  PEGIFQTFTGFHRQFGRNLITQSLFN--FPSMQVCDPKVIEQIMQART-IEKTIIYDFMV 118
            E +F    G  + +G  +    ++    P + + +P+ +E I+ ++  + K+  YD++ 
Sbjct: 78  DE-LFNRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLH 136

Query: 119 PWLGTGLVVSTGTKWAQRRKIITPTFHFKILEDFLVIMNHQTDVLIEKLKQNANSTDFDI 178
           PWLG GL+ ST  KW  RRKI+TP FHFKIL+DF+ + N Q+ VL  KL     S  F++
Sbjct: 137 PWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNL 196

Query: 179 YEHVTYCALDIISESAMGVKLNTQQQPNSEYVMAVKEISDIILKRLFSFLREYKWAFQFT 238
           + +VT C LDI+ E+AMG ++  Q    SEYV AV  I  I+  R      +  + F  T
Sbjct: 197 FPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLT 256

Query: 239 KSHRRQEELVKIVHDFAHNVISERKKQLQDEREQQLTQEKLEEEDVYGKRRMTLLDLLLN 298
             ++  +  +  +H F++ VI ERK +L   +E           D Y             
Sbjct: 257 AEYKLHQSYINTLHGFSNMVIRERKAELAILQENN-NNNNNNAPDAY------------- 302

Query: 299 LEEEDVYGKRRMTLLDLLLNVTIDGKPLSDSDIREEVDTFMFAGHDTTTSCISFAAYYLS 358
              +DV  K+R+  LDLL++ + +G  LS+ DIREEVDTFMF GHDTT++ IS+  + L 
Sbjct: 303 ---DDVGKKKRLAFLDLLIDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLG 359

Query: 359 RDATVQQRVYDEILAIVGPDAKTQELTYGTLQELKYLDMVIKETLRINPSVPIIGRRSAG 418
                Q+RV +E+ +I G D +T   T   L +++YL+  IK++LR+ PSVP++ R    
Sbjct: 360 CHPEYQERVVEELDSIFGDDKET-PATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGE 418

Query: 419 DMLIDGVTIPKGMDFGILIYALHNDPELYPEPARFDPERFSEEASEKRQPYSYIPFSVGA 478
           D+ I G  +P G    I+ YALH +P ++P+P +F+P+ F  E    R P++YIPFS G 
Sbjct: 419 DVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGP 478

Query: 479 RNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKLRIKTDMTLKPVDGAFIKIVPR 534
           RNCIGQ++A+LE K ++  ++  Y++   D R  L +  ++ L+P DG  +KI PR
Sbjct: 479 RNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPR 534



==> Q9VXY0|CP4S3_DROME Probable cytochrome P450 4s3 (EC 1.14.-.-)
           (CYPIVS3) - Drosophila melanogaster (Fruit fly)
          Length = 495

 Score =  322 bits (824), Expect = 3e-087
 Identities = 176/441 (39%), Positives = 266/441 (60%), Gaps = 34/441 (7%)

Query: 95  DPKVIEQIM-QARTIEKTIIYDFMVPWLGTGLVVSTGTKWAQRRKIITPTFHFKILEDFL 153
           DP+ I+Q++   + + K+  Y+ + PWLG GL+ + G  W +RRK++TP FHF+IL +F 
Sbjct: 81  DPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFK 140

Query: 154 VIMNHQTDVLIEKLKQNANSTDFDIYEHVTYCALDIISESAMGVKLNTQQQPNSEYVMAV 213
             M     +L+ +L+  AN   FDIY ++T  ALD I E+AMG+K + Q Q +SEYV AV
Sbjct: 141 EPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDSEYVQAV 200

Query: 214 KEISDIILKRLFSFLREYKWAFQFTKSHRRQEELVKIVHDFAHNVISERKKQLQDEREQQ 273
           + I  ++ K+ FSF +     F+ TK  + +E  +K++HD  + VI  R++QL  ER + 
Sbjct: 201 QSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNE- 259

Query: 274 LTQEKLEEEDVYGKRRMTLLDLLLNLEEEDVYGKRRMTLLDLLLNVTIDGKPLSDSDIRE 333
             + + E++DV  KRR+  LD+LL  + E                    G  LSD+DIRE
Sbjct: 260 -WKPEAEQDDVGAKRRLAFLDMLLLTQME-------------------GGAELSDTDIRE 299

Query: 334 EVDTFMFAGHDTTTSCISFAAYYLSRDATVQQRVYDEILAIVGPDAKTQELTYGTLQELK 393
           EVDTFMF GHDTT+S I+FA   LS++  VQQR ++E   + G +           + + 
Sbjct: 300 EVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREK----------ESMP 349

Query: 394 YLDMVIKETLRINPSVPIIGRRSAGDMLIDGVTIPKGMDFGILIYALHNDPELYPEPARF 453
           YL+ VIKETLRI PSVP   R+   D+ +  +T+PKG     LIY LH DP+ +P+P RF
Sbjct: 350 YLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERF 409

Query: 454 DPERFSEEASEKRQPYSYIPFSVGARNCIGQRYAMLEIKTMLVKLVANYQLLPCDERNKL 513
           DP+RF     ++  P+++  FS G RNCIGQ++AMLE+KT L  L+ +Y+ LP D+ ++ 
Sbjct: 410 DPDRFLVN-EKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLP-DKDHQP 467

Query: 514 RIKTDMTLKPVDGAFIKIVPR 534
           +   ++  K  +G  ++I+PR
Sbjct: 468 KPLAELVTKSGNGIRLRILPR 488